ZHAO Yuxing, DUAN Lian, LYU Wei, YAO Yong, YOU Hui, ZHANG Wen, MA Jin, MAO Xinxin, ZHU Huijuan. Rare Manifestations of Common Diseases: Middle-Aged Male Polyuria-Headache-Inflammatory Granulomatous Lesions[J]. Journal of Rare Diseases, 2023, 2(3): 359-364. DOI: 10.12376/j.issn.2097-0501.2023.03.007
Citation: ZHAO Yuxing, DUAN Lian, LYU Wei, YAO Yong, YOU Hui, ZHANG Wen, MA Jin, MAO Xinxin, ZHU Huijuan. Rare Manifestations of Common Diseases: Middle-Aged Male Polyuria-Headache-Inflammatory Granulomatous Lesions[J]. Journal of Rare Diseases, 2023, 2(3): 359-364. DOI: 10.12376/j.issn.2097-0501.2023.03.007
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Rare Manifestations of Common Diseases: Middle-Aged Male Polyuria-Headache-Inflammatory Granulomatous Lesions

  • 1.

    Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 3.

    Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 4.

    Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 5.

    Department of Rheumatology and Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 6.

    Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 7.

    Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National High Level Hospital Clinical Research Funding 2022-PUMCH-B-016

More Information
  • Corresponding author:

    ZHU Huijuan, E-mail: shengxin2004@163.com

  • Received Date: June 19, 2023
  • Accepted Date: June 29, 2023
  • Available Online: September 08, 2023
2097-0501/©2023 Editorial Office of Journal of Rare Diseases This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/)
    Graphical Abstract
    • Abstract

  • A middle-aged man was presented with poor appetite, polyuria, polydrpsia, and headache. A sellar mass was found, along with total pituitary hypofunction and visual field defect. A biopsy of the lesion via the trans-sphenoidal approach showed inflammatory changes and granuloma formation. However, repeated cerebrospinal fluid and pathogenic examination of the pathological tissue showed no positive indications. The initial diagnosis considered autoimmune hypophysitis, and treatment of glucocorticoids combined with immunosuppressants was administered, which led to a temporary shrinkage of the lesion, but it gradually enlarged subsequently. After multidisciplinary discussion, a high possibility of pituitary tuberculosis infection was decided upon. After standardized anti-tuberculosis treatment was initiated, the lesion reduced noticeably and the patient′s condition improved. Pituitary tuberculosis infection is incredibly rare and extremely easy to misdiagnose. This case was diagnosed and treated in a timely and effective manner through a multidisciplinary approach, highlighting the importance of such an approach in dealing with rare diseases.

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    • References (5)
  • [1]
    Kumar T, Nigam JS, Jamal I, et al. Primary pituitary tuberculosis[J]. Autops Case Rep, 2020, 11: e2020228.
    [2]
    Ben Abid F, Abukhattab M, Karim H, et al. Primary pituitary tuberculosis revisited[J]. Am J Case Rep, 2017, 18: 391-394. doi: 10.12659/AJCR.903233
    [3]
    Srisukh S, Tanpaibule T, Kiertiburanakul S, et al. Pituitary tuberculoma: a consideration in the differential diagnosis in a patient manifesting with pituitary apoplexy-like syndrome[J]. IDCases, 2016, 5: 63-66. doi: 10.1016/j.idcr.2016.07.012
    [4]
    Bonifacio-Delgadillo D, Aburto-Murrieta Y, Salinas-Lara C, et al. Clinical presentation and magnetic resonance findings in sellar tuberculomas[J]. Case Rep Med, 2014, 2014: 961913.
    [5]
    Sharma MC, Arora R, Mahapatra AK, et al. Intrasellar tuberculoma—an enigmatic pituitary infection: a series of 18 cases[J]. Clin Neurol Neurosurg, 2000, 102(2): 72-77. doi: 10.1016/S0303-8467(00)00063-9
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