ZHANG Bin, WU Wei. An Early Onset of Myocardial Infarction Patient with Syphilis and Familial Hypercholesterolemia[J]. Journal of Rare Diseases, 2023, 2(1): 85-87. DOI: 10.12376/j.issn.2097-0501.2023.01.011
Citation: ZHANG Bin, WU Wei. An Early Onset of Myocardial Infarction Patient with Syphilis and Familial Hypercholesterolemia[J]. Journal of Rare Diseases, 2023, 2(1): 85-87. DOI: 10.12376/j.issn.2097-0501.2023.01.011
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An Early Onset of Myocardial Infarction Patient with Syphilis and Familial Hypercholesterolemia

  • 1.

    Department of Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 3.

    State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National High Level Hospital Clinical Research Funding 2022-PUMCH-B-098

More Information
  • Corresponding author:

    WU Wei, E-mail: camsww@163.com

  • Received Date: November 29, 2022
  • Accepted Date: December 25, 2022
  • Available Online: March 06, 2023
2097-0501/©2023 Editorial Office of Journal of Rare Diseases This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/)
    Graphical Abstract
    • Abstract

  • Syphilis may affect the cardiovascular system, in which coronary arteries are less commonly involved. Familial hypercholesterolemia (FH) is an autosomal dominant inherited disease with elevated low-density lipoprotein-cholesterol (LDL-C) levels due to impaired LDL-C clearance. We report a young male patient with syphilis and FH. The clinical manifestations were acute myocardial infarction and high LDL-C levels. Coronary angiography and intracoronary imaging showed multiple aneurysmal ectasia and stenosis. A drug-eluting stent was implemented when recurrent restenosis occurred after two percutaneous coronary drug-eluting balloon angioplasties.

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    • References (10)
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