| Citation: |
Chinese Medical Association Rare Diseases Branch, Hypothalamic and Pituitary Disease Group of China Alliance of Rare Diseases (CARD), Innovation Center of Pituitary Diseases, Peking Union Medical College Hospital. Expert Consensus on Bilateral Inferior Petrosal Sinus Sampling in the Diagnosis of Cushing′s Syndrome (2023)[J]. Journal of Rare Diseases, 2023, 2(3): 365-376. DOI: 10.12376/j.issn.2097-0501.2023.03.008
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Cushing′s syndrome(CS)is a clinical syndrome caused by a variety of causes, with main manifestations exhibited by central obesity, purple skin striae, hypertension, and diabetes. In patients with adrenocorticotropic hormone(ACTH)-dependent CS, the result of bilateral inferior petrosal sinus sampling(BIPSS)is the gold standard for determining the source of ACTH in the absence of routine imaging findings.However, the indications, contraindications, operating procedures, precautions and outcome judgments of BIPSS differ from one medical center to another, and there are currently no international and domestic clinical guidelines and expert consensus on BIPSS. In order to further improve the operation specifications of BIPSS in the diagnosis process of difficult CS, the Hypothalamic and Pituitary Disease Group of the China Alliance for Rare Diseases and the Innovation Center of Pituitary Diseases of Peking Union Medical College Hospital organized experts in endocrinology, interventional radiology, neurosurgery and laboratory in China to formulate this consensus. This consensus aims to provide standardized methodological guidance for the use of BIPSS in the differential diagnostic process of CS in clinical practice.
| [1] |
Crapo L. Cushing′s syndrome: a review of diagnostic tests[J]. Metabolism, 1979, 28(9): 955-977. doi: 10.1016/0026-0495(79)90097-0
|
| [2] |
Mccance DR, Mcilrath E, Mcneill A, et al. Bilateral inferior petrosal sinus sampling as a routine procedure in ACTH-dependent Cushing′s syndrome[J]. Clin Endocrinol (Oxf), 1989, 30(2): 157-166. doi: 10.1111/j.1365-2265.1989.tb03737.x
|
| [3] |
Zampetti B, Grossrubatscher E, Ciaramella PD, et al. Bilateral inferior petrosal sinus sampling[J]. Endocr Connect, 2016, 5(4): R12-R25. doi: 10.1530/EC-16-0029
|
| [4] |
Yanovski JA, Cutler GB, Doppman JL, et al. The limited ability of inferior petrosal sinus sampling with corticotropin-releasing hormone to distinguish Cushing′s disease from pseudo-Cushing states or normal physiology[J]. J Clin Endocrinol Metab, 1993, 77(2): 503-509.
|
| [5] |
Landolt AM, Valavanis A, Girard J, et al. Corticotrophin-releasing factor-test used with bilateral, simultaneous inferior petrosal sinus blood-sampling for the diagnosis of pituitary-dependent Cushing′s disease[J]. Clin Endocrinol (Oxf), 1986, 25(6): 687-696. doi: 10.1111/j.1365-2265.1986.tb03624.x
|
| [6] |
Oldfield EH, Doppman JL, Nieman LK, et al. Petrosal sinus sampling with and without corticotropin-releasing hormone for the differential diagnosis of Cushing′s syndrome[J]. N Engl J Med, 1991, 325(13): 897-905. doi: 10.1056/NEJM199109263251301
|
| [7] |
Oldfield EH, Chrousos GP, Schulte HM, et al. Preopera-tive lateralization of ACTH-secreting pituitary microadenomas by bilateral and simultaneous inferior petrosal venous sinus sampling[J]. N Engl J Med, 1985, 312(2): 100-103. doi: 10.1056/NEJM198501103120207
|
| [8] |
Chen S, Chen K, Wang S, et al. The optimal cut-off of BIPSS in differential diagnosis of ACTH-dependent Cushing′s syndrome: is stimulation necessary?[J]. J Clin Endocrinol Metab, 2020, 105(4): dgz194.
|
| [9] |
Deipolyi AR, Alexander B, Rho J, et al. Bilateral inferior petrosal sinus sampling using desmopressin or corticotropic-releasing hormone: a single-center experience[J]. J Neurointerv Surg, 2015, 7(9): 690-693. doi: 10.1136/neurintsurg-2014-011262
|
| [10] |
Fleseriu M, Auchus R, Bancos I, et al. Consensus on diagnosis and management of Cushing′s disease: a guideline update[J]. Lancet Diabetes Endocrinol, 2021, 9(12): 847-875. doi: 10.1016/S2213-8587(21)00235-7
|
| [11] |
Graham AJ, Gelfand G, Mcfadden SD, et al. Levels of evidence and grades of recommendations in general thoracic surgery[J]. Can J Surg, 2004, 47(6): 461-465.
|
| [12] |
中国研究型医院学会罕见病分会, 中国罕见病联盟, 北京罕见病诊疗与保障学会, 等. Gitelman综合征诊疗中国专家共识(2021版)[J]. 协和医学杂志, 2021, 12(6): 902-912. https://www.cnki.com.cn/Article/CJFDTOTAL-XHYX202106010.htm
|
| [13] |
Jones J, Hunter D. Consensus methods for medical and health services research[J]. BMJ, 1995, 311(7001): 376-380. doi: 10.1136/bmj.311.7001.376
|
| [14] |
Findling JW, Raff H. Cushing′s syndrome: important issues in diagnosis and management[J]. J Clin Endocrinol Metab, 2006, 91(10): 3746-3753. doi: 10.1210/jc.2006-0997
|
| [15] |
Findling JW, Kehoe ME, Raff H. Identification of patients with Cushing′s disease with negative pituitary adrenocorticotropin gradients during inferior petrosal sinus sampling: prolactin as an index of pituitary venous effluent[J]. J Clin Endocrinol Metab, 2004, 89(12): 6005-6009. doi: 10.1210/jc.2004-1378
|
| [16] |
Doppman JL, Oldfield E, Krudy AG, et al. Petrosal sinus sampling for Cushing syndrome: anatomical and technical considerations. Work in progress[J]. Radiology, 1984, 150(1): 99-103. doi: 10.1148/radiology.150.1.6316418
|
| [17] |
Blevins LS, Clark RV, Owens DS. Thromboembolic complications after inferior petrosal sinus sampling in patients with Cushing′s syndrome[J]. Endocr Pract, 1998, 4(6): 365-367. doi: 10.4158/EP.4.6.365
|
| [18] |
Miller DL, Doppman JL. Petrosal sinus sampling: technique and rationale[J]. Radiology, 1991, 178(1): 37-47. doi: 10.1148/radiology.178.1.1845785
|
| [19] |
Bonelli FS, Huston J, Meyer FB, et al. Venous subarachnoid hemorrhage after inferior petrosal sinus sampling for adrenocorticotropic hormone[J]. AJNR Am J Neuroradiol, 1999, 20(2): 306-307.
|
| [20] |
Obuobie K, Davies JS, Ogunko A, et al. Venous thrombo-embolism following inferior petrosal sinus sampling in Cushing′s disease[J]. J Endocrinol Invest, 2000, 23(8): 542-544. doi: 10.1007/BF03343772
|
| [21] |
Gandhi CD, Meyer SA, Patel AB, et al. Neurologic complications of inferior petrosal sinus sampling[J]. AJNR Am J Neuroradiol, 2008, 29(4): 760-765. doi: 10.3174/ajnr.A0930
|
| [22] |
Lefournier V, Martinie M, Vasdev A, et al. Accuracy of bilateral inferior petrosal or cavernous sinuses sampling in predicting the lateralization of Cushing′s disease pituitary microadenoma: influence of catheter position and anatomy of venous drainage[J]. J Clin Endocrinol Metab, 2003, 88(1): 196-203. doi: 10.1210/jc.2002-020374
|
| [23] |
Sheth SA, Mian MK, Neal J, et al. Transsphenoidal surgery for Cushing disease after nondiagnostic inferior petrosal sinus sampling[J]. Neurosurgery, 2012, 71(1): 14-22. doi: 10.1227/NEU.0b013e31824f8e2e
|
| [24] |
Valizadeh M, Ahmadi AR, Ebadinejad A, et al. Diagno-stic accuracy of bilateral inferior petrosal sinus sampling using desmopressin or corticotropic- releasing hormone in ACTH-dependent Cushing′s syndrome: a systematic review and meta-analysis[J]. Rev Endocr Metab Disord, 2022, 23(5): 881-892. doi: 10.1007/s11154-022-09723-y
|
| [25] |
Castinetti F, Morange I, Dufour H, et al. Desmopressin test during petrosal sinus sampling: a valuable tool to discriminate pituitary or ectopic ACTH-dependent Cushing′s syndrome[J]. Eur J Endocrinol, 2007, 157(3): 271-277. doi: 10.1530/EJE-07-0215
|
| [26] |
Heaney AP, Melmed S. Molecular targets in pituitary tumours[J]. Nat Rev Cancer, 2004, 4(4): 285-295. doi: 10.1038/nrc1320
|
| [27] |
Allolio B, Günther RW, Benker G, et al. A multihormonal response to corticotropin-releasing hormone in inferior petrosal sinus blood of patients with Cushing′s disease[J]. J Clin Endocrinol Metab, 1990, 71(5): 1195-1201. doi: 10.1210/jcem-71-5-1195
|
| [28] |
McNally PG, Bolia A, Absalom SR, et al. Preliminary observations using endocrine markers of pituitary venous dilution during bilateral simultaneous inferior petrosal sinus catheterization in Cushing′s syndrome: is combined CRF and TRH stimulation of value?[J]. Clin Endocrinol (Oxf), 1993, 39(6): 681-686. doi: 10.1111/j.1365-2265.1993.tb02427.x
|
| [29] |
De Sousa SMC, Mccormack AI, Mcgrath S, et al. Prolactin correction for adequacy of petrosal sinus cannulation may diminish diagnostic accuracy in Cushing′s disease[J]. Clin Endocrinol (Oxf), 2017, 87(5): 515-522. doi: 10.1111/cen.13401
|
| [30] |
Qiao X, Ye H, Zhang X, et al. The value of prolactin in inferior petrosal sinus sampling with desmopressin stimulation in Cushing′s disease[J]. Endocrine, 2015, 48(2): 644-652. doi: 10.1007/s12020-014-0338-3
|
| [31] |
Grant P, Dworakowska D, Carroll P. Maximizing the accuracy of Inferior petrosal sinus sampling: validation of the use of Prolactin as a marker of pituitary venous effluent in the diagnosis of Cushing′s disease[J]. Clin Endocrinol (Oxf), 2012, 76(4): 555-559. doi: 10.1111/j.1365-2265.2011.04257.x
|
| [32] |
Akbari H, Ghorbani M, Kabootari M, et al. Usefulness of prolactin measurement in inferior petrosal sinus sampling with desmopressin for Cushing′s syndrome[J]. Br J Neurosurg, 2020, 34(3): 253-257. doi: 10.1080/02688697.2020.1736263
|
| [33] |
Jarial KDS, Bhansali A, Mukherjee KK, et al. Prolactin-adjusted ACTH ratio in predicting lateralization of ACTH source during simultaneous bilateral inferior petrosal sinus sampling in patients with Cushing′s disease[J]. Indian J Endocrinol Metab, 2019, 23(1): 56-59. doi: 10.4103/ijem.IJEM_486_18
|
| [34] |
Mulligan GB, Eray E, Faiman C, et al. Reduction of false-negative results in inferior petrosal sinus sampling with simultaneous prolactin and corticotropin measurement[J]. Endocr Pract, 2011, 17(1): 33-40. doi: 10.4158/EP10067.OR
|
| [35] |
Apaydin T, Yasar M, Baltacioglu F, et al. Does concomi-tant prolactin measurement increase the accuracy of inferior petrosal sinus sampling? [J]. Neuroradiology, 2022, 64(7): 1411-1418. doi: 10.1007/s00234-021-02886-6
|
| [36] |
Ishida A, Asakuno K, Shiramizu H, et al. Revalidation of inferior petrosal sinus sampling: the latest results from a single-center experience[J]. Endocr J, 2021, 68(10): 1217-1223. doi: 10.1507/endocrj.EJ21-0156
|
| [37] |
Sharma ST, Raff H, Nieman LK. Prolactin as a marker of successful catheterization during IPSS in patients with ACTH-dependent Cushing′s syndrome[J]. J Clin Endocrinol Metab, 2011, 96(12): 3687-3694. doi: 10.1210/jc.2011-2149
|
| [38] |
Lyu X, Zhang Y, Zhang D, et al. Should we use prolactin adjustment in bilateral inferior petrosal sinus sampling to diagnose Cushing disease? A joint meta-analysis of head-to-head diagnostic tests accuracy studies[J]. Endocr Pract, 2023, 29(4): 254-259. doi: 10.1016/j.eprac.2023.01.008
|
| [39] |
刘湘宁, 崔丽嘉, 陈适, 等. 双侧岩下窦静脉取血假阴性库欣病的临诊应对[J]. 中华内分泌代谢杂志, 2022, 38(1): 50-53.
|
| [40] |
Hayes AR, Grossman AB. Distinguishing Cushing′s disease from the ectopic ACTH syndrome: Needles in a haystack or hiding in plain sight? [J]. J Neuroendocrinol, 2022, 34(8): e13137. doi: 10.1111/jne.13137
|
| [41] |
Wind JJ, Lonser RR, Nieman LK, et al. The lateralization accuracy of inferior petrosal sinus sampling in 501 patients with Cushing′s disease[J]. J Clin Endocrinol Metab, 2013, 98(6): 2285-2293. doi: 10.1210/jc.2012-3943
|
| [42] |
Swearingen B, Katznelson L, Miller K, et al. Diagnostic errors after inferior petrosal sinus sampling[J]. J Clin Endocrinol Metab, 2004, 89(8): 3752-3763. doi: 10.1210/jc.2003-032249
|
| [43] |
Ritzel K, Beuschlein F, Berr C, et al. ACTH after 15 min distinguishes between Cushing′s disease and ectopic Cushing′s syndrome: a proposal for a short and simple CRH test[J]. Eur J Endocrinol, 2015, 173(2): 197-204. doi: 10.1530/EJE-14-0912
|
| [44] |
Wu ZQ, Xu HG. Preanalytical stability of adrenocorticotro-pic hormone depends on both time to centrifugation and temperature[J]. J Clin Lab Anal, 2017, 31(5): e20081.
|
| [45] |
Zerikly RK, Eray E, Faiman C, et al. Cyclic Cushing syndrome due to an ectopic pituitary adenoma[J]. Nat Clin Pract Endocrinol Metab, 2009, 5(3): 174-179.
|
| [46] |
Tsagarakis S, Tsigos C, Vasiliou V, et al. The desmopres-sin and combined CRH-desmopressin tests in the differential diagnosis of ACTH-dependent Cushing′s syndrome: cons-traints imposed by the expression of V2 vasopressin receptors in tumors with ectopic ACTH secretion[J]. J Clin Endocrinol Metab, 2002, 87(4): 1646-1653.
|
| [47] |
Johnston PC, Kennedy L, Weil RJ, et al. Ectopic ACTH-secreting pituitary adenomas within the sphenoid sinus[J]. Endocrine, 2014, 47(3): 717-724. doi: 10.1007/s12020-014-0313-z
|
| [48] |
O'brien T, Young WF, Davilla DG, et al. Cushing′s syndrome associated with ectopic production of corticotrophin-releasing hormone, corticotrophin and vasopressin by a phaeochromocytoma[J]. Clin Endocrinol (Oxf) 1992, 37(5): 460-467. doi: 10.1111/j.1365-2265.1992.tb02359.x
|
| [49] |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 52-1987. A 20-year-old woman with Cushing′s disease and a pulmonary nodule[J]. N Engl J Med, 1987, 317(26): 1648-1658. doi: 10.1056/NEJM198712243172608
|
| [50] |
Perlman JE, Johnston PC, Hui F, et al. Pitfalls in performing and interpreting inferior petrosal sinus sampling: personal experience and literature review[J]. J Clin Endocrinol Metab, 2021, 106(5): e1953-e1967. doi: 10.1210/clinem/dgab012
|
| [51] |
Daousi C, Nixon T, Javadpour M, et al. Inferior petrosal sinus ACTH and prolactin responses to CRH in ACTH-dependent Cushing′s syndrome: a single centre experience from the United Kingdom[J]. Pituitary, 2010, 13(2): 95-104. doi: 10.1007/s11102-009-0200-4
|
| [52] |
Landolt AM, Schubiger O, Maurer R, et al. The value of inferior petrosal sinus sampling in diagnosis and treatment of Cushing′s disease[J]. Clin Endocrinol (Oxf), 1994, 40(4): 485-492. doi: 10.1111/j.1365-2265.1994.tb02487.x
|
| [53] |
Tabarin A, Greselle JF, San-Galli F, et al. Usefulness of the corticotropin-releasing hormone test during bilateral inferior petrosal sinus sampling for the diagnosis of Cushing′s disease[J]. J Clin Endocrinol Metab, 1991, 73(1): 53-59. doi: 10.1210/jcem-73-1-53
|
| [54] |
Bonelli FS, Huston J, Carpenter PC, et al. Adrenocorticotropic hormone-dependent Cushing′s syndrome: sensitivity and specificity of inferior petrosal sinus sampling[J]. AJNR Am J Neuroradiol, 2000, 21(4): 690-696.
|
| [55] |
Ilias I, Chang R, Pacak K, et al. Jugular venous sampl-ing: an alternative to petrosal sinus sampling for the diagnostic evaluation of adrenocorticotropic hormone-depen-dent Cushing′s syndrome[J]. J Clin Endocrinol Metab, 2004, 89(8): 3795-3800. doi: 10.1210/jc.2003-032014
|
| [56] |
Erickson D, Huston J, Young WF, et al. Internal jugular vein sampling in adrenocorticotropic hormone-dependent Cushing′s syndrome: a comparison with inferior petrosal sinus sampling[J]. Clin Endocrinol (Oxf), 2004, 60(4): 413-419. doi: 10.1111/j.1365-2265.2004.01990.x
|
| [57] |
Doppman JL, Oldfield EH, Nieman LK. Bilateral sampling of the internal jugular vein to distinguish between mechanisms of adrenocorticotropic hormone-dependent Cushing syndrome[J]. Ann Intern Med, 1998, 128(1): 33-36. doi: 10.7326/0003-4819-128-1-199801010-00006
|
| [58] |
Teramoto A, Nemoto S, Takakura K, et al. Selective venous sampling directly from cavernous sinus in Cushing′s syndrome[J]. J Clin Endocrinol Metab, 1993, 76(3): 637-641.
|
| [59] |
Burkhardt T, Flitsch J, van Leyen P, et al. Cavernous sinus sampling in patients with Cushing′s disease[J]. Neurosurg Focus, 2015, 38(2): E6. doi: 10.3171/2014.10.FOCUS14687
|
| [60] |
Doppman JL, Nieman LK, Chang R, et al. Selective venous sampling from the cavernous sinuses is not a more reliable technique than sampling from the inferior petrosal sinuses in Cushing′s syndrome[J]. J Clin Endocrinol Metab, 1995, 80(8): 2485-2489.
|
| [61] |
Lodish MB, Keil MF, Stratakis CA. Cushing′s syndrome in pediatrics: an update[J]. Endocrinol Metab Clin North Am, 2018, 47(2): 451-462. doi: 10.1016/j.ecl.2018.02.008
|
| [62] |
Chen S, Chen K, Lu L, et al. The effects of sampling lateralization on bilateral inferior petrosal sinus sampling and desmopressin stimulation test for pediatric Cushing′s disease [J]. Endocrine, 2019, 63(3): 582-591. doi: 10.1007/s12020-018-1779-x
|
| [63] |
Batista D, Gennari M, Riar J, et al. An assessment of petrosal sinus sampling for localization of pituitary microadenomas in children with Cushing disease[J]. J Clin Endocrinol Metab, 2006, 91(1): 221-224. doi: 10.1210/jc.2005-1096
|
| [64] |
Magiakou MA, Mastorakos G, Oldfield EH, et al. Cushing′s syndrome in children and adolescents. Presentation, diagnosis, and therapy[J]. N Engl J Med, 1994, 331(10): 629-636. doi: 10.1056/NEJM199409083311002
|
| [65] |
Joshi SM, Hewitt RJ, Storr HL, et al. Cushing′s disease in children and adolescents: 20 years of experience in a single neurosurgical center[J]. Neurosurgery, 2005, 57(2): 281-285. doi: 10.1227/01.NEU.0000166580.94215.53
|
| [66] |
Storr HL, Alexandraki KI, Martin L, et al. Comparisons in the epidemiology, diagnostic features and cure rate by transsphenoidal surgery between paediatric and adult-onset Cushing′s disease[J]. Eur J Endocrinol, 2011, 164(5): 667-674. doi: 10.1530/EJE-10-1120
|
| [67] |
Lonser RR, Wind JJ, Nieman LK, et al. Outcome of surgical treatment of 200 children with Cushing′s disease[J]. J Clin Endocrinol Metab, 2013, 98(3): 892-901. doi: 10.1210/jc.2012-3604
|
| [68] |
Kang KM, Muralidharan K, Knowlton H, et al. Utility of bilateral inferior petrosal sinus sampling for diagnosis and lateralization of Cushing′s disease in the pediatric population: case series and review of the literature[J]. J Endocrinol Invest, 2022, 45(3): 617-627. doi: 10.1007/s40618-021-01680-8
|
| [69] |
Frete C, Corcuff JB, Kuhn E, et al. Non-invasive diagnostic strategy in ACTH-dependent Cushing′s syndrome[J]. J Clin Endocrinol Metab, 2020, 105(10): dgaa409.
|
| [70] |
Lyu X, Zhang D, Pan H, et al. A noninvasive scoring model for the differential diagnosis of ACTH-dependent Cushing′s syndrome: a retrospective analysis of 311 patients based on easy-to-use parameters[J]. Endocrine, 2022, 78(1): 114-122. doi: 10.1007/s12020-022-03081-0
|
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