Chinese Medical Association Rare Diseases Branch, Hypothalamic and Pituitary Disease Group of China Alliance of Rare Diseases (CARD), Innovation Center of Pituitary Diseases, Peking Union Medical College Hospital. Expert Consensus on Bilateral Inferior Petrosal Sinus Sampling in the Diagnosis of Cushing′s Syndrome (2023)[J]. Journal of Rare Diseases, 2023, 2(3): 365-376. DOI: 10.12376/j.issn.2097-0501.2023.03.008
Citation: Chinese Medical Association Rare Diseases Branch, Hypothalamic and Pituitary Disease Group of China Alliance of Rare Diseases (CARD), Innovation Center of Pituitary Diseases, Peking Union Medical College Hospital. Expert Consensus on Bilateral Inferior Petrosal Sinus Sampling in the Diagnosis of Cushing′s Syndrome (2023)[J]. Journal of Rare Diseases, 2023, 2(3): 365-376. DOI: 10.12376/j.issn.2097-0501.2023.03.008

Expert Consensus on Bilateral Inferior Petrosal Sinus Sampling in the Diagnosis of Cushing′s Syndrome (2023)

Funds: 

National High Leve Hospital Clinical Research Funding 2022-PUMCH-A-015

National High Leve Hospital Clinical Research Funding 2022-PUMCH-B-016

National High Leve Hospital Clinical Research Funding 2022-PUMCH-B-114

The National Key Research and Developmen Program of China 2022YFC3600203

More Information
  • Corresponding authors: ZHU Huijuan1, E-mail: shengxin2004@163.com
    LU Lin1, E-mail: lulin88@sina.com
    ZHANG Xiaobo2, E-mail: pumcradiozxb@163.com

  • Received Date: July 14, 2023
  • Accepted Date: July 24, 2023
2097-0501/©2023 Editorial Office of Journal of Rare Diseases This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/)
  • Cushing′s syndrome(CS)is a clinical syndrome caused by a variety of causes, with main manifestations exhibited by central obesity, purple skin striae, hypertension, and diabetes. In patients with adrenocorticotropic hormone(ACTH)-dependent CS, the result of bilateral inferior petrosal sinus sampling(BIPSS)is the gold standard for determining the source of ACTH in the absence of routine imaging findings.However, the indications, contraindications, operating procedures, precautions and outcome judgments of BIPSS differ from one medical center to another, and there are currently no international and domestic clinical guidelines and expert consensus on BIPSS. In order to further improve the operation specifications of BIPSS in the diagnosis process of difficult CS, the Hypothalamic and Pituitary Disease Group of the China Alliance for Rare Diseases and the Innovation Center of Pituitary Diseases of Peking Union Medical College Hospital organized experts in endocrinology, interventional radiology, neurosurgery and laboratory in China to formulate this consensus. This consensus aims to provide standardized methodological guidance for the use of BIPSS in the differential diagnostic process of CS in clinical practice.

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