<sup>18</sup>F-FET PET在成人高级别胶质瘤诊治中的应用新进展

¹⁸F-FET PET在成人高级别胶质瘤诊治中的应用新进展

摘要: 胶质瘤是成人最常见的原发性颅内肿瘤，其中高级别胶质瘤患者具有生存期短、预后差的特点。高级别胶质瘤的诊断、治疗、疗效评价及预后预测对于改善患者生存有着重要意义。传统增强磁共振成像在定义肿瘤边界、鉴别肿瘤进展与治疗相关改变等方面存在着不足，因此，将氨基酸PET尤其是¹⁸F-FET PET纳入高级别胶质瘤的诊治过程已得到广泛共识。本文对近年来¹⁸F-FET PET在成人高级别胶质瘤的诊断、治疗中的研究新进展进行阐述。

Abstract: Gliomas are the most common primary intracranial tumors in adults, among which high-grade glioma patients are characterized by short survival and poor prognosis. The diagnosis, treatment, evaluation of effective treatments, and prognosis prediction of high-grade gliomas are of great significance for improving patient survival. Conventional enhanced magnetic resonance imaging has deficiencies in delineating tumor extent, identifying tumor progression and treatment-related changes. Therefore, there is a broad consensus to incorporate amino acid PET, and ¹⁸F-FET PET inparticular, into the diagnostic and therapeutic process of high-grade gliomas. In this article, we review the new research progress of ¹⁸F-FET PET in the diagnosis and treatment of adult high-grade glioma in recent years.