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中国血友病骨骼肌肉并发症康复评估与治疗专家共识

中国血友病协作组 中国罕见病联盟血友病学组

中国血友病协作组, 中国罕见病联盟血友病学组. 中国血友病骨骼肌肉并发症康复评估与治疗专家共识[J]. 罕见病研究, 2022, 1(4): 420-427. doi: 10.12376/j.issn.2097-0501.2022.04.010
引用本文: 中国血友病协作组, 中国罕见病联盟血友病学组. 中国血友病骨骼肌肉并发症康复评估与治疗专家共识[J]. 罕见病研究, 2022, 1(4): 420-427. doi: 10.12376/j.issn.2097-0501.2022.04.010
Hemophilia Treatment Center Collaborative Network of China, China Alliance for Rare Diseases, Hemophilia Subcommittee. Expert Consensus on Assessment for Rehabilitation and Treatment of Musculoskeletal Complications of Hemophilia in China[J]. Journal of Rare Diseases, 2022, 1(4): 420-427. doi: 10.12376/j.issn.2097-0501.2022.04.010
Citation: Hemophilia Treatment Center Collaborative Network of China, China Alliance for Rare Diseases, Hemophilia Subcommittee. Expert Consensus on Assessment for Rehabilitation and Treatment of Musculoskeletal Complications of Hemophilia in China[J]. Journal of Rare Diseases, 2022, 1(4): 420-427. doi: 10.12376/j.issn.2097-0501.2022.04.010

中国血友病骨骼肌肉并发症康复评估与治疗专家共识

doi: 10.12376/j.issn.2097-0501.2022.04.010
基金项目: 

中央高水平医院临床科研业务费 2022-PUMCH-B-131

国家重点研发计划资助项目 2016YFC0901500

陈丽霞1, E-mail:clx727@126.com; 张抒扬2,3, E-mail:shuyangzhang@163.com
详细信息
  • 中图分类号: R493;R554+.1

Expert Consensus on Assessment for Rehabilitation and Treatment of Musculoskeletal Complications of Hemophilia in China

Funding: 

National High Level Hospital Clinical Research Funding 2022-PUMCH-B-131

National Key Research and Development Program of China 2016YFC0901500

CHEN Lixia1, E-mail: clx727@126.com; ZHANG Shuyang2, 3, E-mail: shuyangzhang@163.com
  • 摘要: 血友病是一组遗传性出血性疾病,骨骼肌肉出血是最常见表现,是患者致残的重要原因,康复医学在血友病综合管理中发挥了重要的作用,近年来,国内对血友病患者康复评估和治疗的研究增多。基于目前的循证医学证据,多学科领域专家在血友病骨骼肌肉并发症康复评估与治疗方面达成一致共识,为临床规范化诊疗提供了重要依据。

     

  • 表  1  GRADE证据质量分级与定义

    Table  1.   GRADE evidence quality classification and definition

    证据等级 具体描述
    高(A) 非常有把握观察值接近真实值
    中(B) 对观察值有中等把握:观察值有可能接近真实值,但也有可能差别很大
    低(C) 对观察值得把握有限:观察值可能与真实值有很大差别
    极低(D) 对观察值几乎没有把握:观察值与真实值可能有极大差别
    下载: 导出CSV

    表  2  GRADE推荐强度分级与定义

    Table  2.   GRADE recommended strength grading and definition

    推荐强度 具体描述
    强(1) 明确显示干预措施利大于弊或弊大于利
    弱(2) 利弊不确定或无论质量高低的证据显示利弊相当
    下载: 导出CSV

    表  3  不同血友病关节评估量表项目及分值

    Table  3.   Items and scores of different hemophilia joint assessment scales

    Gilbert Colorado PE-1(成人) Colorado PE-0.5(7岁以上儿童) HJHS(4~18岁儿童)
    项目 分值 项目 分值 分值 项目 分值
    肿胀 2 肿胀 3 2 肿胀 3
    - - 肿胀持续时间 1
    肌肉萎缩 1 肌肉萎缩 3 2 肌肉萎缩 2
    轴向畸形 2 轴向畸形 2 2 轴向畸形 -
    活动时骨摩擦音 1 活动时骨摩擦音 3 2 活动时骨摩擦音 2
    活动度 2 活动度 3 2 伸展度丢失 3
    屈曲挛缩 2 屈曲挛缩 3 2 屈曲度丢失 3
    不稳定性 2 不稳定性 2 2 - -
    疼痛 2 疼痛 2 2 疼痛 2
    - - 静息痛 3 3 - -
    - - 步态异常 3 3 步态异常 4
    - - 肌力 2 2 肌力 4
    -不包含该项目
    下载: 导出CSV
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  • 收稿日期:  2022-08-15
  • 录用日期:  2022-08-22
  • 网络出版日期:  2022-12-23

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