Research Progress on the Risk of Venous Thromboembolism in Patients with Hereditary Angioedema

Hereditary angioedema (HAE) is a hereditary disease characterized by recurrent cutaneous and/or submucosal edema. In recent years, it has also been observed that patients with HAE have an increased risk of developing venous thromboembolism (VTE). By systematically reviewing relevant literature, this article aims to explore the mechanisms underlying the increased risk of VTE in patients with HAE, evaluate the impact of existing long-term prophylactic treatments on VTE occurrence in these patients, and further analyze future research directions, thereby providing references for the clinical long-term comprehensive management of HAE patients.