张阳, 张和细, 颜彦. 心包间皮瘤误诊为结核性心包炎一例[J]. 罕见病研究, 2023, 2(1): 105-109. DOI: 10.12376/j.issn.2097-0501.2023.01.014
引用本文: 张阳, 张和细, 颜彦. 心包间皮瘤误诊为结核性心包炎一例[J]. 罕见病研究, 2023, 2(1): 105-109. DOI: 10.12376/j.issn.2097-0501.2023.01.014
ZHANG Yang, ZHANG Hexi, YAN Yan. A Case Report of Pericardial Mesothelioma Misdiagnosed as Tuberculous Pericarditis[J]. Journal of Rare Diseases, 2023, 2(1): 105-109. DOI: 10.12376/j.issn.2097-0501.2023.01.014
Citation: ZHANG Yang, ZHANG Hexi, YAN Yan. A Case Report of Pericardial Mesothelioma Misdiagnosed as Tuberculous Pericarditis[J]. Journal of Rare Diseases, 2023, 2(1): 105-109. DOI: 10.12376/j.issn.2097-0501.2023.01.014

心包间皮瘤误诊为结核性心包炎一例

A Case Report of Pericardial Mesothelioma Misdiagnosed as Tuberculous Pericarditis

  • 摘要: 一例40岁中年男性患者,起病表现为不明原因心包积液,经验性予以抗结核治疗后,期间病情有一过性好转,后逐渐加重发展为缩窄性心包炎、多浆膜腔积液、静脉多发血栓形成。转入复旦大学附属中山医院后通过胸膜组织病理活检证实为胸膜间皮瘤、心包继发恶性肿瘤,后患者病情快速进展,最终死亡。间皮瘤是一类非常罕见的来源于胸膜及其他部位的恶性肿瘤。患者初诊时多为晚期,治疗手段有效,中位生存期短。加强对间皮瘤的认识,重视各项医技检查,尤其是动态随访病情变化对本病早期诊断具有重要价值。

     

    Abstract: A 40-year-old male patient presented with an unexplained pericardial effusion and was treated with antituberculosis therapy. This patient showed a transient improvement, but then progressively worsened to develop constrictive pericarditis, multiple plasma chamber effusions, and venous thrombosis. The patient was transferred to Zhongshan Hospital, Fudan University. Through a pleural histopathological biopsy, this patient was diagnosed with pleural mesothelioma and secondary malignant tumor of the pericardium. Later, clinical the manifestations of patient progressed rapidly, resulting in the death of the patient. Mesothelioma is a very rare group of malignant tumors originating from the pleura and other tissues. Patients are mostly advanced at the time of initial diagnosis, with limited treatments and short median survival. It is important to strengthen the understanding of mesothelioma, pay attention to all medical and technical examinations, especially dynamic follow-up of changes in the disease for early diagnosis of this disease.

     

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